Rheumatology

The Immunological Basis in the Pathogenesis of Gout

Reparative radiological changes of hip joint after TNF inhibitors in ankylosing spondylitis

Background: Hip involvement in ankylosing spondylitis (AS) is a common extraspinal arthritic manifestation, which is associated to a worse functional outcome. Little data are available on the effectiveness of conservative treatment strategies. The TNF inhibitors have been proven effective on AS activity parameters. Their structural effect on hip disease however, little is studied. Case pres...

Pulmonary nodules in a patient with rheumatoid arthritis: Which diagnostic approach is the most appropiate?

Background: Pulmonary nodular excavation should firstly evoke tuberculosis or necrosis broncho-pulmonary tumor, particularly: epidermoid carcinoma. The case discussed here illustrated these difficulties in patients with rheumatoid arthritis (RA). Case Presentation: A 63-year-old woman was presented with a-three-year history of RA and a recent discovery of an excavated pulmonary nodule. Initi...

How Much Improvement is Expected in Ocular Lesions of Behçet's Disease Treated with Pulse Cyclophosphamide?

Background: The natural history of ocular lesions in Behçet's disease is toward severe loss of vision/blindness in few years, whereas cytotoxic drugs have changed the outcome. Several open labeled cohort studies showed pulse cyclophosphamide (PCP) to be the best choice. Since one third of these patients are resistant to PCP it is important to know how much improvement one can expect from the r...

Prevalence of fibromyalgia in patients referring to Kerman rheumatology clinic from 1995 to 1998

  fibromyalgia(FM), a chronic musculoskeletal syndrome,is charaterized by widespread pain and multiple tenderness in the body.clinical studies show a wide range of prevalence(1% to 20%). there is no published data about the prevalence of FM in Kerman.in this descriptive study demographic variables and the final clhnical diognosis of 8270 cases referring to Kerman rheumatology clinic from 1995 ...

Estimating the prevalence and disease characteristics of rheumatoid arthritis in Tehran: A WHO -ILAR COPCORD Study (from Iran COPCORD study, Urban Study stage 1)

  Background :To estimate the prevalence and characteristics of Rheumatoid Arthritis (RA) in an urban area of Tehran.   Methods : A total of 50 clusters were randomly selected in Tehran and 10291 subjects completed the COPCORD Core Questionnaire during 2004 and 2005. Patients with rheumatic complaints were examined and diagnosed by subspecialty fellows in rheumatology. Laboratory and radiology ...